New Synthetic Process Developed at Yale University Will Allow Scientists to Examine a Critical Link Associated with Diabetes, Inflammation and Human Aging
MOUNTAIN VIEW, Calif. — October 15, 2015 — A new study funded by the SENS Research Foundation sheds greater light on diabetes and aging through a synthetic process developed at Yale University. The new process will allow researchers to study glucosepane, a key molecule involved in diabetes, inflammation, and human aging.
Glucosepane is considered to be a critical chemical link in both diabetes and aging. It is also an independent risk factor for long-term microvascular complications in diabetes. In an article published this week in the journal Science, senior author David Spiegel and his colleagues describe the new synthesis, as well as a new synthetic methodology, which may have applications beyond the current research.